Division of Cardiology, Terrence Donnelly Heart Centre, St Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada. University of Toronto, Toronto, Canada. Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada. Division of Cardiac Surgery, St Michael's Hospital, Toronto, Canada. Department of Anesthesia, St Michael's Hospital, Toronto, Canada. Division of Endocrinology and Metabolism, St Michael's Hospital, Toronto, Canada. Department of Internal Medicine, Discipline of Cardiology, State University of Campinas, Campinas, Brazil. Heart Health Institute, Toronto, ON, Canada. Department of Medical Imaging, St. Michael's Hospital, Toronto, Canada. Trillium Health Partners, Toronto, Canada. Division of Cardiology, Terrence Donnelly Heart Centre, St Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada. kim.connelly@unityhealth.to. University of Toronto, Toronto, Canada. kim.connelly@unityhealth.to. Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada. kim.connelly@unityhealth.to. Division of Cardiology, Terrence Donnelly Heart Centre, St Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada. andrew.yan@unityhealth.to. University of Toronto, Toronto, Canada. andrew.yan@unityhealth.to. Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada. andrew.yan@unityhealth.to.